Otic pit

Otic pit

Section through the head of a human embryo, at the beginning of the fourth week, in the region of the hind-brain.
Latin	fovea otica
Gray's	subject #228 1029
Precursor	auditory plate
Code	TE E5.15.2.0.0.0.5

The auditory pit, also known as the otic pit, is the first rudiment of the internal ear. It appears shortly after that of the eye, in the form of a patch of thickened ectoderm, the auditory plate, over the region of the hind-brain. The auditory plate becomes depressed and converted into the auditory pit (or otic pit^[1]).

References

^ hednk-010 — Embryology at UNC

This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained within it may be outdated.

Prenatal development/Mammalian development of nervous system (GA 9.733 and GA 10.1002, TE E5.13-16)

Neurogenesis

General neural development/ neurulation/neurula	Notochord · Neuroectoderm · Neural plate (Neural fold, Neural groove)

Neural crest	Cranial neural crest (Cardiac neural crest complex) · Truncal neural crest

Neural tube	Rostral neuropore Neuromere/Rhombomere Cephalic flexure · Pontine flexure Alar plate (sensory) · Basal plate (motor) Glioblast · Neuroblast Germinal matrix

Eye development

Neural tube: Optic vesicle · Optic stalk · Optic cup

Surface ectoderm: Lens placode

Auditory development

Otic placode (Otic pit, Otic vesicle)

note: NS is mostly ectoderm, but mesoderm is precursor for epineurium, perineurium, and endoneurium

M: CNS

anat(n/s/m/p/4/e/b/d/c/a/f/l/g)/phys/devp

noco(m/d/e/h/v/s)/cong/tumr, sysi/epon, injr

proc, drug(N1A/2AB/C/3/4/7A/B/C/D)

M: EYE

anat(g/a/p)/phys/devp/prot

noco/cong/tumr, epon

proc, drug(S1A/1E/1F/1L)

M: EAR

anat(e/p)/phys/devp

noco/cong, epon

proc, drug(S2)